25 KG/BAG White Powder P Toluenesulfonic Acid CAS 104-15-4 For Making Cresol And Medicine

25 KG/BAG White Powder P Toluenesulfonic Acid CAS 104-15-4 For Making Cresol And Medicine

Introduction

P Toluenesulfonic Acid (Its molecular structural formula is p-CH3C6H4SO3H, also known as TsOH, English name is P Toluenesulfonic Acid) referred to as PTS, is a non-oxidizing organic acid, white needle or powder crystals, soluble in water, alcohols and other polar solvents. Easy deliquescence, easy to make wood, cotton fabric dehydration and carbonization, insoluble in benzene and toluene. generating p-cresol when alkali fusion. Commonly, P Toluenesulfonic Acid monohydrate (TsOHH2O) or tetrahydrate (TsOH4H2O) is preferred.
Preparation of methyl p-cresol acid in industry is by using concentrated sulfuric acid on the toluene sulfonation of P Toluenesulfonic Acid. The preparated P Toluenesulfonic Acid often contains benzene sulfonic acid and sulfuric acid impurities, can be purified in recrystallization of concentrated hydrochloric acid, azeotropic drying.

Parameter

Usage

P Toluenesulfonic Acid is widely used as catalyst agent in the synthesis of pharmaceuticals, pesticides, polymerization stabilizer and organic synthesis (esters, etc.), paint intermediates and resin curing agent. And it is also the commonly used acid catalyst in organic synthesis. It is neutralized with sodium hydroxide and then obtains sodium P Toluenesulfonate, and react with phosphorus pentachloride, can obtains p-toluenesulfonyl chloride. The latter used in the nucleophilic substitution reaction, also used as alcohol hydroxyl protective group. p-CH3C6H4SO3Na + PCl5 →p-CH3C6H4SO2Cl.
The use of p-toluenesulfonic acid also catalyzes the protection of dihydrofuran on the alcohol, carboxylic acid esterification, transesterification reaction, making the aldehyde generate acetal.