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Product Details:
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Odor: | Pungent | Boiling Point: | 107.25°C (rough Estimate) |
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Appearance: | White Crystalline Solid | Molecular Formula: | (CH2O)n |
Cas Number: | 30525-89-4 | Other Name: | Polyoxymethylene |
Purity: | ≥ 96% | Hazards: | May Cause Skin And Eye Irritation |
Stability: | Stable Under Normal Conditions | Solubility In Water: | Soluble |
Melting Point: | 120-170 °C (lit.) | Color: | White |
Application: | Used As A Cross-linking Agent, Preservative, And Disinfectant | Storage Condition: | Store In A Cool, Dry Place |
Class: | 4.1 | Refractive Index: | 1.4540 (estimate) |
25 KG/BAG Paraformaldehyde PFA Molecular Weight 90.08
Paraformaldehyde (PFA) is the smallest polyoxymethylene, the polymerization product of formaldehyde with a typical degree of polymerization of 8–100 units. Paraformaldehyde commonly has a slight odor of formaldehyde due to decomposition. Paraformaldehyde is a poly-acetal.
White combustible crystalline powder with formaldehyde odor. The melting point was 121-123 °c. Flash point 71.1 °c. Spontaneous ignition point 300. Slowly soluble in cold water, dissolved in hot water faster. Formaldehyde is released in aqueous solution. The solubility in water is 0. 24g/looc3h2 0 at 20 ℃. Insoluble in ethanol. Soluble in caustic soda, potassium solution.
Paraformaldehyde (PFA) is the smallest polyoxymethylene, the poly
Items | Specification | Result |
APPEARANCE | WHITE POWDER | WHITE POWDER |
CONTENT | 96±1% | 96.86% |
ACID VALUE(FORMIC ACID) | ≤ 0.03% | 0.02% |
CARBINOL | ≤ 0.05% | 0.03% |
ASH | ≤ 0.03% | 0.01% |
Once paraformaldehyde is depolymerized, the resulting formaldehyde may be used as a fumigant, disinfectant, fungicide, and fixative. Longer chain-length (high molecular weight) polyoxymethylenes are used as a thermoplastic and are known as polyoxymethylene plastic (POM, Delrin). It was used in the past in the discredited Sargenti method of root canal treatment.
Paraformaldehyde is not a fixative; it must be depolymerized to formaldehyde in solution. In cell culture, a typical formaldehyde fixing procedure would involve using a 4% formaldehyde solution in phosphate buffered saline (PBS) on ice for 10 minutes. In histology and pathology specimens preparation, usually, the fixation step is performed using 10% Neutral Buffered Formalin (4% formaldehyde) for, at least, 24 hours.
Paraformaldehyde is also used to crosslink proteins to DNA, as used in ChIP (chromatin immunoprecipitation) which is a technique to determine which part of DNA certain proteins are binding to.
Paraformaldehyde can be used as a substitute of aqueous formaldehyde to produce the resinous binding material, which is commonly used together with melamine, phenol or other reactive agents in the manufacturing of particle board, medium density fiberboard and plywood.
As a formaldehyde releasing agent, paraformaldehyde is a potential carcinogen. Its acute oral median lethal dose in rats is 592 mg/kg.
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